Q10 Co-enzyme Q10 (Co-Q10) is a fat-soluble, vitamin-like co-enzyme that is found in the energy producing metabolic pathways of virtually all cells of the human body, thus earning Co-Q10 its other name, ubiquinone.
Co-Q10 is critical in the synthesis of ATP (the energy "currency" of all cells). This process takes place in the mitochondria and involves a complex cascade of enzymatic reactions. Co-Q10 is also noted for its powerful antioxidant activity, and keeps other antioxidants in their reduced active states. Co-Q10 also stabilizes cell membranes and platelets.
Doctors have been using Co-Q10 concurrently with standard medication for addressing the symptoms of congestive heart failure for the last four decades. In fact, Co-Q10 has been approved as a drug in Japan for the treatment of congestive heart failure since 1974, with a number of other nations following suite.
Placebo-controlled studies to date with Co-Q10 have produced what scientists call 'significantly positive results', including diminished levels of fatigue, chest pain, dyspnea and palpitations. Treatment with Co-Q10 was even able to restore normal heart size and function in some of these patients - primarily those whose onset of congestive heart failure was relatively recent.
Studies have also examined the effects of Co-Q10 supplementation as an adjunct to conventional drug therapies for hypertension. A critical point to remember is that Co-Q10 is fat-soluble, and that absorption of Co-Q10 has always been a challenge. For this reason it is highly recommended that Co-Q10 be taken with a meal that contains essential fats, such as olive oil or fish.
Adult Dosage: Take one to three capsules daily with a fat containing meal, or as directed by a qualified health care practitioner.
Warnings and Precautions: CoQ10 may decrease the effectiveness of warfarin; consult a health care practitioner prior to taking this supplement if you are on warfarin.